What is Subutex (Buprenomorphine)?
Subutex (Buprenomorphine) contains a substance close to morphine. In addicts with heroin or other opiates, it suppresses the symptoms of withdrawal that occur during drug deprivation, and which are largely the cause of addiction.
It is used in drug addicts as an opiate substitution product. Its prescription supplements a medical, social and psychological care, essential to limit the risk of relapse
Presentations of the drug SUBUTEX
SUBUTEX 0.4 mg:
SUBUTEX 2 mg:
SUBUTEX 8 mg:
Active ingredients: Buprenorphine, Buprenorphine hydrochloride
Common Excipients: Citric Acid Anhydrous, Corn Starch, Lactose Monohydrate, Magnesium Stearate, Mannitol, Povidone K 30
Other excipients (specific to certain forms): Sodium citrate, Sodium citrate anhydrous
Contraindications to the drug SUBUTEX
This medicine should not be used in the following cases:
severe liver failure,
severe respiratory failure,
during a state of acute drunkenness or delirium tremens,
in combination with methadone, morphine and related substances
child under 15 years old.
Interactions of the drug SUBUTEX with other substances
This medicine must not be combined with methadone or strong analgesics (morphine and its derivatives): risk of diminishing their effects.
It can interact with antitussives and analgesics of the opioid family (codeine, tramadol, ethylmorphine …).
In addition, inform your doctor or pharmacist if you are taking sedative medications.
There is no known interaction with cocaine (frequently used by drug addicts mixed with heroin).
Fertility, pregnancy and lactation
The use of this medicine in the treatment of opioid dependence is possible during pregnancy. Dose adjustment may be necessary. In case of prolonged intake at the end of pregnancy, reinforced medical surveillance of the newborn is recommended in order to prevent a possible withdrawal syndrome.
This medicine passes weakly in breast milk. Only your doctor can appreciate the need for treatment and its risk during breastfeeding.
Instructions for use and dosage of the drug SUBUTEX
This drug must be taken sublingually: placed under the tongue, it melts in contact with saliva and is absorbed by the oral mucosa; it must be kept under the tongue for 5 to 10 minutes, the usual time for its complete dissolution.
The daily dose is taken at one time; it remains active for 24 hours.
Initially, the doctor prescribes between 0.8 and 4 mg; he then adapts the dosage according to the result. The maximum dosage is 16 mg per day.
Precautions are necessary during the first set (see Caution). When this medication is taken in combination with methadone treatment, the dose of methadone should be reduced to a maximum of 30 mg per day.
When the status of the addict is stabilized, the doctor gradually decreases the dosage until the treatment is stopped.
The side effects
When the mode of administration is sublingual, the most commonly reported adverse effects are related to the opioid action of HDB: headache, dizziness, orthostatic hypotension, insomnia, drowsiness, asthenia, constipation, nausea and vomiting, sweating. If you can not stand these side effects, there is the possibility of turning to methadone